体内由S-磺化γ-球蛋白重建完整γ-球蛋白
Reconstruction of intact gamma-globulin from S-sulfonated gamma-globulin in vivo.
作者信息
Masuho Y, Tomibe K, Matsuzawa K, Watanabe T, Ishimoto S
出版信息
J Biochem. 1976 Jun;79(6):1377-9. doi: 10.1093/oxfordjournals.jbchem.a131192.
Abstract
The conversion of the S-surfonate group in a peptide to a disulfide bond has been observed in vitro. This paper reports that the conversion of this group in human S-sulfonated gamma-globulin (S-GG) appeared to occur in vivo judging from the change in molecular weight of S-GG observed in the presence of sodium dodecyl sulfate (SDS) and the restoration of hemolytic activity.
摘要
在体外已观察到肽中的S-磺酸盐基团可转化为二硫键。本文报道，从在十二烷基硫酸钠（SDS）存在下观察到的人S-磺化γ-球蛋白（S-GG）分子量变化以及溶血活性的恢复情况判断，该基团在体内似乎也会发生转化。
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