Abdel-Aal Y A
Arch Exp Veterinarmed. 1977;31(4):465-70.
Two kinetic evidences revealed that two cholinesterase forms are present in rat brain homogenate and involved in the hydrolysis of acetylthiocholine. These two kinetic forms have different affinity to acetylthiocholine (34 fold), and different sensitivity to carbofuran, 2,2-dimethyl 2,3-dihadro-7-benzofuranyl methylcarbamate (33 fold). The proportion of the enzyme in each kinetic form is 0.52 form I and 0.48 form II.
两项动力学证据表明，大鼠脑匀浆中存在两种胆碱酯酶形式，并参与硫代乙酰胆碱的水解。这两种动力学形式对硫代乙酰胆碱的亲和力不同（相差34倍），对克百威（2,2-二甲基-2,3-二氢-7-苯并呋喃基甲基氨基甲酸酯）的敏感性也不同（相差33倍）。每种动力学形式的酶比例分别为：形式I占0.52，形式II占0.48。
