Kielstein P, Martin J, Janetschke P
Arch Exp Veterinarmed. 1977;31(4):609-19.
Pasteurella can be isolated from about 50 per cent of pneumonically changed pig lungs. Isolation, however, is possible also from intact lungs of conventional or secondary SPF animals. The authors of this paper used the positive hyaluronidase test and identified exclusively Pasteurella multocida, with predominance of capsular type A. Most of the Pasteurella strains tested in this context caused pneumonia in SPF animals, particularly, following intratracheal application. No correlations were found to exist with murine virulence, the serological type or the origin of the strains from affected or intact lungs. Apart from virulence differences between the strains, host reactivity was found to depend primarily on high germ counts and, under natural conditions, on environmental stresses. Pasteurella multocida, hence, can be considered as one of the potential pathogens of porcine pneumonia. Pneumonia foci with transduced localised fibrinous pleuritis are characteristic and constitute a process of purulent inflammation with early involvement of fibrin.
约50%发生肺炎病变的猪肺中可分离出多杀性巴氏杆菌。然而，从常规或二级无特定病原体（SPF）动物的正常肺中也有可能分离出该菌。本文作者采用透明质酸酶阳性试验，仅鉴定出多杀性巴氏杆菌，其中以A型荚膜为主。在此背景下测试的大多数巴氏杆菌菌株在SPF动物中引发肺炎，尤其是经气管内接种后。未发现与鼠类毒力、血清型或菌株源自患病或正常肺之间存在相关性。除菌株间毒力差异外，发现宿主反应主要取决于高菌量，在自然条件下还取决于环境压力。因此，多杀性巴氏杆菌可被视为猪肺炎的潜在病原体之一。伴有转导性局限性纤维素性胸膜炎的肺炎病灶具有特征性，构成了一个脓性炎症过程，早期有纤维蛋白参与。
