Jacob J, Grimmer G
J Lipid Res. 1967 Jul;8(4):308-11.
Positional isomers of hexadecenoic aud octadecenoic acids of human adipose tissue have been separated by gas-liquid chromatography and their amounts determined by oxidative cleavage (MnO(4) and IO(4)). The following isomeric octadecenoic acids were present: 7-octadecenoic acid (0.4%), 8- (1.9%), 9- (73.0%), 10- (2.5%), 11- (19.0%) and 12- (3.2%). The hexadecenoic acids have also been shown to be a mixture of positional isomers, in which the cis-9-isomer predominates. 10-Hexadecenoic and 12-octadecenoic acids could conceivably be precursors of linoleic acid. The following branched fatty acids have also been determined in human depot fat: 13-methyltetradecanoic, 12-methyltetradecanoic, 14-methylpentadecanoic, 14-methylhexadecanoic, and 16-methylheptadecanoic acid. They were present in percentages of 0.02-0.6% and their identification rests solely on comparison of their gas-liquid chromatographic retention times with those of synthetic compounds.
已通过气液色谱法分离出人脂肪组织中十六碳烯酸和十八碳烯酸的位置异构体，并通过氧化裂解（MnO(4) 和 IO(4)）测定了它们的含量。存在以下十八碳烯酸异构体：7-十八碳烯酸（0.4%）、8-（1.9%）、9-（73.0%）、10-（2.5%）、11-（19.0%）和 12-（3.2%）。十六碳烯酸也已被证明是位置异构体的混合物，其中顺式-9-异构体占主导。10-十六碳烯酸和 12-十八碳烯酸可以想象是亚油酸的前体。在人体储存脂肪中还测定了以下支链脂肪酸：13-甲基十四烷酸、12-甲基十四烷酸、14-甲基十五烷酸、14-甲基十六烷酸和 16-甲基十七烷酸。它们的含量为 0.02 - 0.6%，其鉴定仅基于将其气液色谱保留时间与合成化合物的保留时间进行比较。
