Beretta P, Sartori F
Arch Sci Med (Torino). 1977 Jul-Sep;134(3):329-36.
Calcium dobesylate was administered for 30 days to diabetics with or without clinical signs referable to microangiopathy and increased capillary fragility unaccompanied by coagulation and haemostasis disturbances. Good results were observed in 90% of cases. It is felt that the drug can also be used in the tertiary prevention of systemic microangiopathy, as well as the medical management of diabetic retinopathy.
对患有或未患有可归因于微血管病的临床症状且毛细血管脆性增加但无凝血和止血障碍的糖尿病患者,给予甲磺酸多贝酯治疗30天。90%的病例观察到良好效果。认为该药物也可用于全身性微血管病的三级预防以及糖尿病视网膜病变的药物治疗。