St John Sutton M G, Traill T A, Ghafour A S, Brown D J, Gibson D G
Br Heart J. 1977 Dec;39(12):1283-91. doi: 10.1136/hrt.39.12.1283.
In order to investigate the functional effects of mitral valve surgery, echocardiograms showing left ventricular dimension were recorded and digitised in 14 normal subjects and 129 patients after mitral valve surgery. Measurements were made of peak rate of increase of dimension (dD/dt) and duration of rapid filling, studies on left ventriculograms in 36 patients having shown close correlation between these values and changes in cavity volume. In 14 patients with mitral stenosis, peak dD/dt was reduced to 7-2 +/ 1-5 cm/s, and filling period prolonged to 330 +/- 65 ms, compared with normal (16-0 +/- 3-2 cm/s, and 160 +/- 50 ms, respectively), and after mitral valvotomy, these values improved significantly (10-4 +/- 2-7 cm/s and 245 +/- 55 ms). Characteristic abnormalities were found in 67 patients with mitral prostheses. Values for the Björk-Shiley (10-5 +/- 4-2 cm/s and 180 +/- 80 ms) and Hancock (10-3 +/- 3-7 cm/s, 245 +/- 80 ms) values were similar, and both superior to the Starr-Edwards (7-4 +/- 3-0 cm/s, 295 +/- 105 ms). Results after mitral valve repair in 30 cases were not significantly different from normal (14-4 +/- 5-0 cm/s, 170 +/- 50 ms). Values outside the 95 per cent confidence limits for the valve in question allowed diagnosis of value malfunction in 18 cases. The method is value in comparing different operative procedures and in following up patients after mitral valve surgery.
为了研究二尖瓣手术的功能效果,对14名正常受试者和129例二尖瓣手术后患者记录并数字化显示左心室大小的超声心动图。测量了尺寸增加的峰值速率(dD/dt)和快速充盈持续时间,对36例患者的左心室造影研究表明,这些值与腔室容积变化之间存在密切相关性。在14例二尖瓣狭窄患者中,与正常情况(分别为16.0±3.2cm/s和160±50ms)相比,峰值dD/dt降至7.2±1.5cm/s,充盈期延长至330±65ms,二尖瓣切开术后,这些值显著改善(10.4±2.7cm/s和245±55ms)。在67例二尖瓣人工瓣膜患者中发现了特征性异常。Björk-Shiley瓣膜(10.5±4.2cm/s和180±80ms)和Hancock瓣膜(10.3±3.7cm/s,245±80ms)的值相似,且均优于Starr-Edwards瓣膜(7.4±3.0cm/s,295±105ms)。30例二尖瓣修复术后的结果与正常情况无显著差异(14.4±5.0cm/s,170±50ms)。所讨论瓣膜的95%置信限之外的值可诊断18例瓣膜功能障碍。该方法对于比较不同的手术操作以及二尖瓣手术后对患者进行随访很有价值。