Fukukawa K, Matsuura T, Endo N, Kunishige H, Tohara M, Watanabe T, Matsukubo H, Tsuji Y, Ijichi H
Br Heart J. 1979 Aug;42(2):176-81. doi: 10.1136/hrt.42.2.176.
In order to establish a new echocardiographic index of the severity of mitral stenosis, left ventricular echocardiograms were digitised using manual tracing and a computer. The instantaneous left ventricular dimension was measured in 15 patients with mitral stenosis. The peak rate of change of left ventricular dimension (peak dD/dt) and the normalised peak rate (peak dD/dt/D) during early diastole were significantly lower in mitral stenosis than in normal subjects. Also, the time between the second heart sound and peak dD/dt was significantly shorter in patients with mitral stenosis than in normal subjects. Correlation between the mitral valve area calculated from the Gorlin formula and peak dD/dt/D was good, while valve area was poorly correlated with the EF slope of the anterior mitral leaflet echo. It is suggested that by continuous measurement of left ventricular dimension and of its first derivative, the reduced atrioventricular blood flow in mitral stenosis can be shown, and that peak dD/dt/D during early diastole is a possible index of its severity.
为建立二尖瓣狭窄严重程度的新超声心动图指标,使用手动追踪和计算机对左心室超声心动图进行数字化处理。对15例二尖瓣狭窄患者测量了瞬时左心室尺寸。二尖瓣狭窄患者舒张早期左心室尺寸的峰值变化率(峰值dD/dt)和标准化峰值率(峰值dD/dt/D)显著低于正常受试者。此外,二尖瓣狭窄患者第二心音与峰值dD/dt之间的时间明显短于正常受试者。根据戈林公式计算的二尖瓣面积与峰值dD/dt/D之间相关性良好,而瓣膜面积与二尖瓣前叶回声的EF斜率相关性较差。建议通过连续测量左心室尺寸及其一阶导数,可显示二尖瓣狭窄时房室血流减少,舒张早期的峰值dD/dt/D可能是其严重程度的一个指标。