Zaynoun S T, Hunter J A, Darby F J, Zarembski P, Johnson B E, Frain-Bell W
Br J Dermatol. 1977 Dec;97(6):663-8. doi: 10.1111/j.1365-2133.1977.tb14274.x.
In a group of 19 subjects suffering from erythropoietic protoporphyria the administration of beta-carotene appeared to produce improvement based on a subjective assessment of alterations in exposure times required to produce the symptoms and signs of the condition. This clinical improvement however failed to show a direct correlation with the prophyrin levels in blood and faeces, or with the estimation by phototesting of the minimal response dose within the action spectrum of 400-600 nm.
在一组19名患有红细胞生成性原卟啉症的受试者中，根据对引发该病症症状和体征所需暴露时间变化的主观评估，β-胡萝卜素的给药似乎产生了改善效果。然而，这种临床改善并未显示出与血液和粪便中的卟啉水平，或与通过光测试对400 - 600纳米作用光谱内最小反应剂量的估计值之间存在直接关联。
