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小脑疾病中的注视障碍、眼球漂移运动和向心性眼球震颤。

Gaze failure, drifting eye movements, and centripetal nystagmus in cerebellar disease.

作者信息

Leech J, Gresty M, Hess K, Rudge P

出版信息

Br J Ophthalmol. 1977 Dec;61(12):774-81. doi: 10.1136/bjo.61.12.774.

DOI:10.1136/bjo.61.12.774
PMID:603785
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1043118/
Abstract

Three abnormalities of eye movement in man are described which are indicative of cerebellar system disorder, namely, centripetally beating nystagmus, failure to maintain lateral gaze either in darkness or with eye closure, and slow drifting movements of the eyes in the absence of fixation. Similar eye movement signs follow cerebellectomy in the primate and the cat. These abnormalities of eye movement, together with other signs of cerebellar disease, such as rebound alternating, and gaze paretic nystagmus, are explained by the hypothesis that the cerebellum helps to maintain lateral gaze and that brain stem mechanisms which monitor gaze position generate compensatory biases in the absence of normal cerebellar function.

摘要

本文描述了人类三种眼部运动异常,这些异常表明小脑系统功能紊乱,即向心性眼球震颤、在黑暗中或闭眼时无法维持侧方凝视,以及在无注视时眼球缓慢漂移运动。灵长类动物和猫在小脑切除术后也会出现类似的眼部运动体征。这些眼部运动异常,连同小脑疾病的其他体征,如反弹交替和凝视麻痹性眼球震颤,都可以用以下假设来解释:小脑有助于维持侧方凝视,并且在缺乏正常小脑功能时,监测凝视位置的脑干机制会产生代偿性偏差。

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本文引用的文献

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["Recovery nystagmus" after unilateral vestibular prolapse, a process related to Bechterew nystagmus].单侧前庭脱垂后的“恢复性眼球震颤”,一种与别赫捷列夫眼球震颤相关的过程
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Accuracy of saccadic eye movements and maintenance of eccentric eye positions in the dark.黑暗中眼球扫视运动的准确性及偏中心眼位的维持
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The effect of cerebellectomy on the cat's bestibulo-ocular integrator.小脑切除对猫前庭眼整合器的影响。
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Neuronal activity in the prepositus hypoglossi nucleus correlated with vertical and horizontal eye movement in the cat.
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Ocular motor abnormalities in hereditary cerebellar ataxia.遗传性小脑共济失调中的眼球运动异常。
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8
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