磷酸盐补充对大鼠完整及骨折股骨的影响：一项生物力学研究。
Effects of phosphate supplementation on intact and fractured femora of rats: a biomechanical study.
作者信息
Dzioba R B, Jackson R W
出版信息
Can Med Assoc J. 1977 Nov 19;117(10):1173-5.
Abstract
The production of a better and stronger healing bone has attracted the interest of many investigators in the past. Numerous substances have been used to increase both the strength and the rate of production of fracture callus. Recently phosphate, administered orally, has been suggested for this purpose. A biomechanical study was conducted with rat femora and variable doses of phosphate in this regard. Phosphate was found to benefit osteomalacic bones but to have no effect on normal bones and a toxic effect in high concentrations.
摘要
过去，生成更好更强壮的愈合骨吸引了许多研究者的关注。许多物质已被用于提高骨折骨痂的强度和生成速率。最近，有人建议口服磷酸盐用于此目的。在这方面，对大鼠股骨和不同剂量的磷酸盐进行了一项生物力学研究。结果发现，磷酸盐对骨软化骨有益，但对正常骨无影响，且在高浓度时有毒性作用。
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