腺苷氨基水解酶。2-和6-取代嘌呤核糖核苷以及9-取代腺嘌呤核苷的结合与水解。 - Suppr

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超能文献

Adenosine aminohydrolase. Binding and hydrolysis of 2-and 6-substituted purine ribonucleosides and 9-substituted adenine nucleosides.

作者信息

Chassy B M, Suhadolnik R J

出版信息

J Biol Chem. 1967 Aug 25;242(16):3655-8.

PMID:6038494

Abstract

摘要

相似文献

Adenosine aminohydrolase. Binding and hydrolysis of 2-and 6-substituted purine ribonucleosides and 9-substituted adenine nucleosides.腺苷氨基水解酶。2-和6-取代嘌呤核糖核苷以及9-取代腺嘌呤核苷的结合与水解。

J Biol Chem. 1967 Aug 25;242(16):3655-8.

On the rate-determining step in the action of adenosine deaminase.

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Substrate properties of cycloadenosines with adenosine aminohydrolase as evidence for the conformation of enzyme-bound adenosine.

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Substrate binding by adenosine deaminase. Specificity, pH dependence, and competition by mercurials.

J Biol Chem. 1967 Mar 10;242(5):977-83.

On the mechanism of adenosine deaminase action.关于腺苷脱氨酶的作用机制

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Alkylation of adenosine deaminase by benzylbromoacetate and 9-(p-bromoacetamidobenzyl)adenine.腺苷脱氨酶被溴乙酸苄酯和9-(对溴乙酰氨基苄基)腺嘌呤烷基化。

Biochim Biophys Acta. 1970 Jun 10;206(3):414-25. doi: 10.1016/0005-2744(70)90157-9.

Ring-modified substrates of adenosine deaminases.

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Specificity of inhibition of adenosine deaminase by trialcohols derived from nucleosides.

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Enzyme inhibitors. XX. Studies on the hydrophobic and hydroxyl binding regions of adenosine deaminase. 9-(2-m-Bromoacetamidophenethyl)adenine, a new irreversible inhibitor of adenosine deaminase.酶抑制剂。XX。腺苷脱氨酶疏水及羟基结合区域的研究。9-(2-间溴乙酰氨基苯乙基)腺嘌呤，一种新型不可逆腺苷脱氨酶抑制剂。

J Med Chem. 1968 Jan;11(1):21-6. doi: 10.1021/jm00307a004.

N6-(delta 2-isopentenyl)adenosine: its conversion to inosine, catalyzed by adenosine aminohydrolases from chicken bone marrow and calf intestinal mucosa.N6-（δ2-异戊烯基）腺苷：由鸡骨髓和小牛肠黏膜中的腺苷氨基水解酶催化其转化为肌苷。

Can J Biochem. 1971 Jun;49(6):623-30. doi: 10.1139/o71-089.

引用本文的文献

Enzymatic Synthesis of 2-Chloropurine Arabinonucleosides with Chiral Amino Acid Amides at the C6 Position and an Evaluation of Antiproliferative Activity In Vitro.用手性氨基酸酰胺在 C6 位对 2-氯嘌呤阿拉伯糖苷进行酶法合成及其体外抗增殖活性评价。

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Synthesis and anti-HIV activity of (-)-beta-D-(2R,4R)-1,3-dioxolane-2,6-diamino purine (DAPD) (amdoxovir) and (-)-beta-D-(2R,4R)-1,3-dioxolane guanosine (DXG) prodrugs.（-）-β-D-（2R，4R）-1,3-二氧戊环-2,6-二氨基嘌呤（DAPD）（安多昔韦）和（-）-β-D-（2R，4R）-1,3-二氧戊环鸟苷（DXG）前药的合成及抗HIV活性

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The role of divalent cations in structure and function of murine adenosine deaminase.二价阳离子在小鼠腺苷脱氨酶结构与功能中的作用。

Protein Sci. 1997 May;6(5):1031-7. doi: 10.1002/pro.5560060509.

Localization of purine metabolizing enzymes in bovine brain microvessel endothelial cells: an enzymatic blood-brain barrier for dideoxynucleosides?嘌呤代谢酶在牛脑微血管内皮细胞中的定位：二脱氧核苷的酶促血脑屏障？

Pharm Res. 1996 Dec;13(12):1881-6. doi: 10.1023/a:1016001712524.

Rat cerebral-cortex adenosine deaminase activity and its subcellular distribution.大鼠大脑皮层腺苷脱氨酶活性及其亚细胞分布。

Biochem J. 1974 Oct;144(1):37-41. doi: 10.1042/bj1440037.

Studies on the coronary dilator actions of some adenosine analogues.某些腺苷类似物的冠状动脉扩张作用研究。

Br J Pharmacol. 1974 Jan;50(1):25-33. doi: 10.1111/j.1476-5381.1974.tb09589.x.

Adenosine deaminase activity associated with phagocytic vacuoles. Cytochemical demonstration by electron microscopy.与吞噬泡相关的腺苷脱氨酶活性。电子显微镜细胞化学显示。

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Ecto-enzyme activity of human erythrocyte adenosine deaminase.

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Lipophilic halogenated congeners of 2',3'-dideoxypurine nucleosides active against human immunodeficiency virus in vitro.2',3'-二脱氧嘌呤核苷的亲脂性卤代同系物在体外对人类免疫缺陷病毒具有活性。

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Cosolvent-buffer mixtures as models for the cytoplasmic mileu: the enzymology of adenosine aminohydrolase.作为细胞质环境模型的助溶剂-缓冲液混合物：腺苷氨基水解酶的酶学

Mol Cell Biochem. 1976 Aug 30;12(2):93-101. doi: 10.1007/BF01731555.

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