Myers R M, Carey D E
Science. 1967 Sep 15;157(3794):1307-8. doi: 10.1126/science.157.3794.1307.
Chikungunya virus and dengue type 2 virus were isolated from a single blood specimen taken from a patient in the acute phase of a dengue-like illness seen at Christian Medical College Hospital, Vellore, South India, in October 1964. In serial blood specimens collected from this patient there was an increase in antibody to these same two viruses. The technique for unmasking an agent (such as dengue) with a long incubation period in mice in the presence of an agent with a short incubation period is described.
1964年10月,在印度南部韦洛尔的基督教医学院医院,从一名患有登革热样疾病急性期患者的单一血液标本中分离出基孔肯雅病毒和2型登革热病毒。在从该患者采集的系列血液标本中,针对这两种相同病毒的抗体有所增加。本文描述了在存在潜伏期短的病原体的情况下,在小鼠中揭示潜伏期长的病原体(如登革热)的技术。