Knorpp C T, Merchant W R, Gikas P W, Spencer H H, Thompson N W
Science. 1967 Sep 15;157(3794):1312-3. doi: 10.1126/science.157.3794.1312.
Studies in vitro indicate that hydroxyethyl starch is an effective extracellular cryoprotective agent for erythrocytes. It is as effective as polyvinylpyrrolidone in cryophylactic ability. It is degraded to glucose units in the circulation, is not retained in tissues, and is inexpensive to produce. Changes in the size and degree of hydroxyethylation of the branched-chain starch may result in a more effective cryoprotective agent.
体外研究表明，羟乙基淀粉是一种有效的红细胞细胞外冷冻保护剂。其冷冻保护能力与聚乙烯吡咯烷酮相当。它在循环中降解为葡萄糖单位，不会在组织中蓄积，且生产成本低廉。支链淀粉的大小和羟乙基化程度的改变可能会产生一种更有效的冷冻保护剂。
