Nicholson K G, Lawford C V, Tyrrell D A
Dev Biol Stand. 1977;39:129-34.
Measurements of peak flow, vital capacity, FEV1 and flow volume studies were performed in healthy volunteers for 20 weeks following intranasal vaccination with live-attenuated A/Victoria/3/75 recombinants or placebo. Despite differing attenuation of the two candidate strains, no effect on pulmonary function was detected.
在健康志愿者中,用减毒活A/维多利亚/3/75重组体或安慰剂进行鼻内接种后20周,测量了峰值流量、肺活量、第一秒用力呼气量(FEV1)并进行了流量容积研究。尽管两种候选毒株的减毒程度不同,但未检测到对肺功能的影响。