流感疫苗在豚鼠体内的抗卵清蛋白致敏能力。
Anti-ovalbumin sensitizing ability of influenza vaccines in guinea pigs.
作者信息
Weeke-Lüttmann M, Schramm-Thiel N
出版信息
Dev Biol Stand. 1977;39:219-222.
PMID:604100
Abstract
The anti-ovalbumin sensitizing ability of four highly purified commercial influenza vaccines was tested in guinea pigs by means of passive cutaneous anaphylaxis. Aluminimum-adsorbed and fluid vaccines as well as pretreatments by one or two subcutaneous inoculations were compared. The two adsorbed vaccines induced significant sensitization after just one inoculation while the two fluid vaccines revealed their sensitizing ability almost exclusively after repeated administration.
摘要
通过被动皮肤过敏反应，在豚鼠身上测试了四种高度纯化的市售流感疫苗的抗卵清蛋白致敏能力。比较了铝吸附疫苗和液体疫苗，以及通过一次或两次皮下接种进行的预处理。两种吸附疫苗仅接种一次后就引起了显著的致敏作用，而两种液体疫苗几乎仅在反复接种后才显示出其致敏能力。
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