Herbein J H, Martin R J, Griel L C, Kavanaugh J F
Growth. 1977 Dec;41(4):277-83.
Growth hormone (GH), insulin, cortisol, triiodothyronine (T3) and thyroxine (T4) were determined in serum of fetal pigs at 90, 100, 110 and 114 days of gestation and of newborn pigs at 1 and 24 hours of age. Fetal GH, T3 and cortisol increased between 90 and 110 days. GH concentration decreased between 110 and 114 days, while T3 and cortisol were unchanged. T4 was variable in fetal pigs and no relationship with T3 levels was apparent. Fetal insulin was constant at approximately 10 muU/ml. In newborn pigs there was a 3-fold and 2-fold increase in T3 and T4, respectively, during the first 24 hours of life. Cortisol in serum more than doubled during the first hour. Between 1 and 24 hours, there was a simultaneous decrease in cortisol and a 6-fold increase in insulin. No significant change in GH was noted during this time. Intraperitoneal insulin injected one hour before sacrifice induced a hypoglycemic response in newborn pigs, but not in fetal pigs.
在妊娠90、100、110和114天的胎猪以及出生1小时和24小时的新生猪血清中测定了生长激素（GH）、胰岛素、皮质醇、三碘甲状腺原氨酸（T3）和甲状腺素（T4）。胎猪的GH、T3和皮质醇在90至110天之间升高。GH浓度在110至114天之间下降，而T3和皮质醇无变化。胎猪的T4变化不定，与T3水平无明显关系。胎猪胰岛素恒定在约10 μU/ml。新生猪在出生后的头24小时内，T3和T4分别增加了3倍和2倍。血清皮质醇在出生后的第一小时内增加了一倍多。在1至24小时之间，皮质醇同时下降，胰岛素增加了6倍。在此期间未观察到GH有显著变化。在处死前1小时腹腔注射胰岛素可诱导新生猪出现低血糖反应，但对胎猪无此作用。
