Olek K, Wardenbach P
J Clin Chem Clin Biochem. 1977 Dec;15(12):657-62.
With a glass-capillary column 20 aromatic acids, probably present in urine, were analysed quantitatively. In comparison with a packed column the capillary column offers several advantages: a higher resolution; a greatly reduced analysis time, an increased sensitivity. Though a split system is used, repeatability and linearity are suitable for quantitative analysis. The advantages are best recognized by the analysis of urine specimens of patients with a metabolic disorder (phenylketonuria).
使用玻璃毛细管柱对可能存在于尿液中的20种芳香酸进行了定量分析。与填充柱相比,毛细管柱具有几个优点:更高的分辨率;大大缩短的分析时间;更高的灵敏度。尽管使用了分流系统,但重复性和线性仍适用于定量分析。通过对患有代谢紊乱(苯丙酮尿症)患者的尿液标本进行分析,这些优点得到了最好的体现。