Job C K, Chacko C J, Taylor P M
Lepr India. 1977 Oct;49(4):467-71.
Biopsies from 2 patients clinically diagnosed and confirmed by histopathological studies as histoid leprosy were examined using and electronmicroscope. The cells that form the nodule are found to contain far more solid bacilli and much less electron transparent substance than those in lepromatous lesions. They have the characteristics of both macrophages and fibroblasts. It is reasonable to conclude that they are histiocytes produced by local multiplication in response to stimulation by rapidly proliferating M. leprae rather than from accumulation of blood monocytes at the site of inflammation as lepromatous lesions.
对2例临床诊断为类瘤型麻风并经组织病理学研究确诊的患者的活检组织进行了电子显微镜检查。发现形成结节的细胞所含的坚实杆菌比瘤型麻风病变中的细胞多得多，而电子透明物质则少得多。它们具有巨噬细胞和成纤维细胞的特征。可以合理地得出结论，它们是由局部增殖产生的组织细胞，是对快速增殖的麻风杆菌刺激的反应，而不是像瘤型麻风病变那样由炎症部位的血液单核细胞积聚形成的。
