Hughesdon P E
J Pathol. 1976 Aug;119(4):201-9. doi: 10.1002/path.1711190404.
A series of 114 ovaries form women aged 20 to 82 showed cortical islands of endometrial stroma in about two-thirds of those over 40. This identity was commonly apparent in ordinary sections and was confirmed in half the affected ovaries by the presence of K cells (endometrial granulocytes) in one or more foci; it may be masked by attenuation or conversion into smooth muscle. The islands show transitional forms to decidual foci and to cortical granulomata and related leucocytic lesions, a few of which also showed K cells: they are ultimately converted into weakly orceinophil hyaline foci which are common in later life and showed K cells in four instances and continuity with stromal islands in 20 ovaries. The lesions appear to arise from the implantation of endometrial stroma into the ovary, the surface of which becomes more cellular and probably more permeable after 40. The islands may foster the development of cortical stromal hyperplasia and their antecedents that of surface epithelial tumours.
对114名年龄在20岁至82岁之间女性的卵巢进行研究，结果显示，在40岁以上的女性中，约三分之二的卵巢存在子宫内膜间质皮质岛。在普通切片中，这种特征通常很明显，并且在一半受影响的卵巢中，通过一个或多个病灶中存在K细胞（子宫内膜粒细胞）得以证实；它可能会因变薄或转化为平滑肌而被掩盖。这些岛状结构呈现出向蜕膜病灶、皮质肉芽肿及相关白细胞病变的过渡形式，其中少数也显示有K细胞：它们最终会转化为弱嗜orcein的透明病灶，这种病灶在晚年很常见，在4例中显示有K细胞，在20个卵巢中与间质岛相连。这些病变似乎源于子宫内膜间质植入卵巢，40岁以后卵巢表面细胞增多，可能通透性也增加。这些岛状结构可能促进皮质间质增生的发展，而其前身可能促进表面上皮肿瘤的发展。
