新生大鼠肝脏中氨基酸的糖异生作用。
Gluconeogenesis from amino acids in neonatal rat liver.
作者信息
Yeung D, Oliver I T
出版信息
Biochem J. 1967 Jun;103(3):744-8. doi: 10.1042/bj1030744.
Abstract
- The utilization of amino acids for gluconeogenesis by rat liver develops in postnatal life, reaching maximum activity at the fifth day. 2. The activity of aspartate transaminase shows a similar trend in postnatal development and the increased activity appears to be due to the soluble enzyme. 3. The activity of alanine transaminase is low in foetal and postnatal rat liver and increases in activity at about the twentieth day. 4. Aspartate, glutamate and alanine make a major contribution to gluconeogenesis in the postnatal rat liver.
摘要
- 大鼠肝脏利用氨基酸进行糖异生的功能在出生后逐渐发展，在出生后第5天达到最大活性。2. 天冬氨酸转氨酶的活性在出生后发育过程中呈现相似趋势，其活性增加似乎归因于可溶性酶。3. 丙氨酸转氨酶在胎儿和出生后大鼠肝脏中的活性较低，在大约第20天活性增加。4. 天冬氨酸、谷氨酸和丙氨酸在出生后大鼠肝脏的糖异生过程中起主要作用。
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本文引用的文献
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