视前区注射血管紧张素对下丘脑外侧部单位活动的影响。

Effect of preoptic administration of angiotensin on lateral hypothalamic unit activity.

作者信息

Kucharczyk J, Mogenson G

出版信息

Physiol Behav. 1977 Sep;19(3):455-7. doi: 10.1016/0031-9384(77)90297-9.

Abstract

The effect of administering angiotensin II to the preoptic region on lateral hypothalamic single unit activity was studied in unanesthetized, freely-moving rats. Angiotensin (100 ng) reliably initiated drinking behavior and caused an increase in the discharge frequency of single neurons located in the perifornical area but had no effect on units in the zona incerta, ventromedial hypothalamus or farlateral hypothalamus. These results suggest that efferent pathways from preoptic receptors for angiotensin pass through the midlateral hypothalamus.

摘要

在未麻醉、自由活动的大鼠中，研究了向视前区注射血管紧张素II对下丘脑外侧单个单位活动的影响。血管紧张素（100纳克）能可靠地引发饮水行为，并使位于穹窿周区的单个神经元放电频率增加，但对未定带、腹内侧下丘脑或下丘脑最外侧区的神经元没有影响。这些结果表明，视前区血管紧张素受体的传出通路经过下丘脑中外侧区。