Gaymans R, Haverkorn M J, Valkenburg H A, Goslings W R
Lancet. 1976 Sep 25;2(7987):674-7. doi: 10.1016/s0140-6736(76)92478-8.
In a Dutch general practice the adult female population was screened for asymptomatic bacteriuria (A.B.) by repeated urine culture after vulval cleansing. The prevalence of signficant A.B. was 4.7% and increased with age. Women with significant A.B. were followed up for one year. All symptomatic urinary-tract infections were recorded during the same period (incidence 59 per 1000 population). Women with significant A.B. at screening were divided into three groups according to the pattern of the follow-up results: transitory A.B., symptomatic A.B., and persistent A.B. The last group differed from the penultimate group with regare to the site of their urinary-tract involvement, symptomatic cases having predominantly upper-urinary-tract involvement and persistent cases lower-urinary-tract infection. In the matched control group the acquisition-rate of both symptomatic and asymptomatic 0acteriuria was over 12%, a figure similar to the percentage of women present in the practice population during one year with transient, symptomatic, and persistent A.B. Screening for A.B. in the general non-pregnant female population is not advocated at present. Screening and treatment of existing A.B. should be carried out in pregnant women who run an increased risk.
在荷兰的一家普通诊所，通过对外阴进行清洁后反复进行尿培养，对成年女性人群进行无症状菌尿（A.B.）筛查。显著A.B.的患病率为4.7%，且随年龄增长而增加。对患有显著A.B.的女性进行了为期一年的随访。在同一时期记录了所有有症状的尿路感染（发病率为每1000人中有59例）。根据随访结果模式，将筛查时患有显著A.B.的女性分为三组：暂时性A.B.、有症状A.B.和持续性A.B.。最后一组与倒数第二组在尿路受累部位方面存在差异，有症状的病例主要是上尿路受累，而持续性病例是下尿路感染。在匹配的对照组中，有症状和无症状菌尿的获得率均超过12%，这一数字与该诊所一年中存在暂时性、有症状和持续性A.B.的女性百分比相似。目前不主张对一般非妊娠女性人群进行A.B.筛查。对于有增加风险的孕妇，应进行现有A.B.的筛查和治疗。
