Collis K A, Stark A J
Res Vet Sci. 1977 Nov;23(3):326-30.
The activities of eight enzymes (glutamate dehydrogenase, sorbital dehydrogenase, malate dehydrogenase, lactate dehydrogenase, alpha-hydroxy butyrate dehydrogenase, gamma-glutamyl transpeptidase, alkaline phosphatase and creatine kinase) were determined in tissue homogenates of liver, kidney, spleen, lung, small intestine, cardiac muscle and skeletal muscle, from 15 Large White pigs of three different ages (1.5 weeks, 18--22 weeks and 113 weeks). The results showed that variation in tissue enzyme concentration due to differences in sex is minimal. Variation due to differences in age, however, appears to be of greater importance, particularly when considering young animals. These age differences may affect the interpretation of plasma enzyme changes due to tissue damage, and the use of additional enzyme assays as an aid to interpretation in these cases is advisable.
测定了来自15头三个不同年龄（1.5周、18 - 22周和113周）的大白猪的肝脏、肾脏、脾脏、肺、小肠、心肌和骨骼肌组织匀浆中八种酶（谷氨酸脱氢酶、山梨醇脱氢酶、苹果酸脱氢酶、乳酸脱氢酶、α - 羟基丁酸脱氢酶、γ - 谷氨酰转肽酶、碱性磷酸酶和肌酸激酶）的活性。结果表明，性别差异导致的组织酶浓度变化极小。然而，年龄差异导致的变化似乎更为重要，尤其是在考虑幼龄动物时。这些年龄差异可能会影响因组织损伤导致的血浆酶变化的解读，在这些情况下，建议使用额外的酶测定来辅助解读。
