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犬杏仁核的细胞构筑与乙酰胆碱酯酶活性

Cytoarchitecture and acetylcholinesterase activity of the amygdaloid nuclei in the dog.

作者信息

Kosmal A, Nitecka L

出版信息

Acta Neurobiol Exp (Wars). 1977;37(6):363-74.

PMID:605824
Abstract

The cellular structure and distribution of histochemically demonstrated acetylcholinesterase (AChE) activity were studied in the amygdaloid body of 9 dogs. Cytoarchitectonic observations were made in series of paraffin and celloidin sections stained with cresyl violet. For the demonstration of the acetylcholinesterase activity, modifications of Koelle method were used. The general pattern of morphological structure of the dog's amygdaloid body is similar to that in other mammalian species. The corticomedial group of the nuclei was characterized generally by cytoarchitectonic uniformity of small, lightly stained cells and low intensity of the AChE reaction, except for the nucleus of the lateral olfactory tract and the lateral part of the central nucleus. The latter showed further differentiation in both cellular arrangement and distribution of AChE activity and may be divided into three subdivisions. The basolateral group of nuclei was characterized by higher differentiation of the cellular arrangement and distribution of the AChE activity. The highest enzyme activity was observed in the basal magnocellular nucleus. These findings support the homology of particular amygdaloid nuclei in various mammalian species.

摘要

研究了9只犬杏仁核中组织化学显示的乙酰胆碱酯酶(AChE)活性的细胞结构和分布。在经甲酚紫染色的石蜡切片和火棉胶切片系列中进行细胞构筑观察。为显示乙酰胆碱酯酶活性,采用了对Koelle方法的改良。犬杏仁核的形态结构总体模式与其他哺乳动物相似。核的皮质内侧组通常以小的、淡染细胞的细胞构筑均匀性和AChE反应强度低为特征,但外侧嗅束核和中央核外侧部分除外。后者在细胞排列和AChE活性分布上都有进一步分化,可分为三个亚区。核的基底外侧组以细胞排列和AChE活性分布的更高分化为特征。在基底大细胞核中观察到最高的酶活性。这些发现支持了不同哺乳动物物种中特定杏仁核的同源性。

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