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人体杏仁核中乙酰胆碱酯酶活性的定位

Localization of acetylcholinesterase activity in the amygdaloid body of man.

作者信息

Nitecka L, Narkiewicz O

出版信息

Acta Neurobiol Exp (Wars). 1976;36(3):333-51.

PMID:970243
Abstract

The localization of acetylcholinesterase (AChE) activity in the nuclei of the amygdaloid body of man was studied by Gerebtzoff's modification of Koelle's acetylthiocholine method on 10 human brains. To compare the histochemical results with the cytoarchitectionics, additionally sections from 10 human brains were stained with cresyl violet. The intensity of AChE activity in the different amygdaloid nuclei varied widely. The high AChE activity occurred in the basal lateral nucleus and in the lateral part of the central nucleus. Very little activity was found in the medial nucleus and in the intermediate part of the central nucleus. All remaining nuclei showed AChE activity of moderate intensity. In almost each amygdaloid nucleus, differences of AChE activity among various areas were observed. In the amygdala of man all nuclei described in animals were found except nucleus of the lateral olfactory tract. Most of the human amygdaloid nuclei show more differentiated structure than in lower mammals in terms of not only cytoarchitectonic subdivision, but also in the intensity of AChE activity.

摘要

采用Gerebtzoff对Koelle乙酰硫代胆碱法的改良方法,对10例人脑杏仁体细胞核中的乙酰胆碱酯酶(AChE)活性定位进行了研究。为了将组织化学结果与细胞构筑学进行比较,另外对10例人脑的切片进行了甲酚紫染色。不同杏仁核中AChE活性的强度差异很大。高AChE活性出现在基底外侧核和中央核的外侧部分。在内侧核和中央核的中间部分发现的活性非常低。其余所有核均显示中等强度的AChE活性。在几乎每个杏仁核中,都观察到不同区域之间AChE活性的差异。在人类杏仁核中,除了外侧嗅束核外,发现了动物中描述的所有核。就细胞构筑细分以及AChE活性强度而言,大多数人类杏仁核的结构比低等哺乳动物更具分化性。

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