• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Tissue distribution of chloroquine, hydroxychloroquine, and desethylchloroquine in the rat.

作者信息

McChesney E W, Banks W F, Fabian R J

出版信息

Toxicol Appl Pharmacol. 1967 May;10(3):501-13. doi: 10.1016/0041-008x(67)90089-0.

DOI:10.1016/0041-008x(67)90089-0
PMID:6059665
Abstract
摘要

相似文献

1
Tissue distribution of chloroquine, hydroxychloroquine, and desethylchloroquine in the rat.氯喹、羟氯喹和去乙基氯喹在大鼠体内的组织分布
Toxicol Appl Pharmacol. 1967 May;10(3):501-13. doi: 10.1016/0041-008x(67)90089-0.
2
Metabolism of chloroquine and hydroxychloroquine in albino and pigmented rats.氯喹和羟氯喹在白化病大鼠和有色大鼠体内的代谢
Toxicol Appl Pharmacol. 1965 Jul;7(4):627-36. doi: 10.1016/0041-008x(65)90050-5.
3
Tissue distribution of chloroquine in the rabbit.氯喹在兔体内的组织分布
Arch Int Pharmacodyn Ther. 1970 Apr;184(2):366-73.
4
Tissue distribution of subcutaneously administered chloroquine in the rat.皮下注射氯喹在大鼠体内的组织分布
Arzneimittelforschung. 1971 Apr;21(4):573-4.
5
Tissue distribution of chloroquine in the rat.
Acta Physiol Acad Sci Hung. 1968;34(4):319-25.
6
Studies of the metabolism of some compounds of the 4-amino-7-chloroquinoline series.4-氨基-7-氯喹啉系列某些化合物的代谢研究。
J Pharmacol Exp Ther. 1966 Mar;151(3):482-93.
7
Tissue distribution of chloroquine in rats in the course of long-term application.
Arch Int Pharmacodyn Ther. 1972 May;197(1):45-52.
8
Tissue distribution and urinary excretion of chloroquine in rats.氯喹在大鼠体内的组织分布及尿排泄情况
Arzneimittelforschung. 1972 Jan;22(1):82-8.
9
Tissue distribution of chloroquine and hydroxychloroquine in rats.氯喹和羟氯喹在大鼠体内的组织分布
Acta Univ Palacki Olomuc Fac Med. 1982;102:99-105.
10
Animal toxicity and pharmacokinetics of hydroxychloroquine sulfate.硫酸羟氯喹的动物毒性和药代动力学
Am J Med. 1983 Jul 18;75(1A):11-8. doi: 10.1016/0002-9343(83)91265-2.

引用本文的文献

1
Mechanisms Underlying the Effects of Chloroquine on Red Blood Cells Metabolism.氯喹对红细胞代谢影响的作用机制。
Int J Mol Sci. 2024 Jun 11;25(12):6424. doi: 10.3390/ijms25126424.
2
Hydroxychloroquine-induced Retinal Toxicity.羟氯喹诱导的视网膜毒性。
Front Pharmacol. 2023 May 30;14:1196783. doi: 10.3389/fphar.2023.1196783. eCollection 2023.
3
A linked physiologically based pharmacokinetic model for hydroxychloroquine and metabolite desethylhydroxychloroquine in SARS-CoV-2(-)/(+) populations.用于 SARS-CoV-2(-)/(+) 人群中羟氯喹及其代谢物去乙基羟氯喹的链接生理药代动力学模型。
Clin Transl Sci. 2023 Jul;16(7):1243-1257. doi: 10.1111/cts.13527. Epub 2023 Apr 29.
4
The Challenges of Predicting Drug-Induced QTc Prolongation in Humans.预测药物致 QT 间期延长在人体中的挑战。
Toxicol Sci. 2022 Apr 26;187(1):3-24. doi: 10.1093/toxsci/kfac013.
5
Systemic toxicity of chloroquine and hydroxychloroquine: prevalence, mechanisms, risk factors, prognostic and screening possibilities.氯喹和羟氯喹的全身毒性:流行情况、机制、危险因素、预后和筛查可能性。
Rheumatol Int. 2021 Jul;41(7):1189-1202. doi: 10.1007/s00296-021-04868-6. Epub 2021 Apr 24.
6
Does hydroxychloroquine still have any role in the COVID-19 pandemic?羟氯喹在 COVID-19 大流行中还有作用吗?
Expert Opin Pharmacother. 2021 Jul;22(10):1257-1266. doi: 10.1080/14656566.2021.1898589. Epub 2021 Mar 16.
7
Physiologically Based Pharmacokinetics of Lysosomotropic Chloroquine in Rat and Human.溶酶体靶向性氯喹在大鼠和人体中的生理药代动力学。
J Pharmacol Exp Ther. 2021 Feb;376(2):261-272. doi: 10.1124/jpet.120.000385. Epub 2020 Dec 4.
8
How Could In Vitro Antiviral Activity Be Applied to Optimize the Dosing Regimens of Candidates for the Treatment of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)?如何将体外抗病毒活性应用于优化严重急性呼吸综合征冠状病毒2(SARS-CoV-2)治疗候选药物的给药方案?
Clin Infect Dis. 2021 Jul 15;73(2):352-353. doi: 10.1093/cid/ciaa1325.
9
Lysosomal Biogenesis and Implications for Hydroxychloroquine Disposition.溶酶体生物发生及其对羟氯喹处置的影响。
J Pharmacol Exp Ther. 2021 Feb;376(2):294-305. doi: 10.1124/jpet.120.000309. Epub 2020 Nov 10.
10
A multi centre randomized open label trial of chloroquine for the treatment of adults with SARS-CoV-2 infection in Vietnam.越南一项关于氯喹治疗成人新型冠状病毒肺炎感染的多中心随机开放标签试验。
Wellcome Open Res. 2020 Jun 12;5:141. doi: 10.12688/wellcomeopenres.15936.1. eCollection 2020.