体外抗体形成需要两种细胞类型。
A requirement for two cell types for antibody formation in vitro.
作者信息
Mosier D E
出版信息
Science. 1967 Dec 22;158(3808):1573-5. doi: 10.1126/science.158.3808.1573.
PMID:6060362
Abstract
A suspension of mouse spleen cells can be separated into two populations on the basis of their ability or inability to adhere to plastic dishes. It was found that both adherent and nonadherent cells were necessary for the induction of antibody formation to sheep red blood cells in vitro. Exposure of adherent cells to antigen for brief periods of time was sufficient to initiate a maximal in vitro response.
摘要
小鼠脾细胞悬液可根据其能否黏附于塑料培养皿分为两类细胞群。研究发现，在体外诱导针对绵羊红细胞的抗体形成时，贴壁细胞和非贴壁细胞都是必需的。将贴壁细胞短时间暴露于抗原足以引发最大程度的体外反应。
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