Egyed M N, Williams M C
Avian Dis. 1977 Oct-Dec;21(4):566-75.
Two-week-old straight-run white broiler chicks and 2-week-old straight-run white turkey poults were fed seed or whole plants Cymopterus watsonii or seed of Cymopterus longipes at 0.4, 0.8, and 1.6% of body weight, and then placed in sunlight for 5 hours each day for 7 days. All plant material produced moderate to severe photosensitivity in chicks. Toxic signs included photophobia; red discoloration of beak, comb, and feet; loss of feathers in the periorbital area; dried serous fluid on comb and edge of beak; keratoconjunctivitis; and multiple lesions on feet and legs. Turkey poults showed a syndrome similar to that of chicks. Mortality was particularly high in turkeys fed C. longipes seed. Toxic signs in turkeys 6 weeks after treatment included tremors in the legs; upturning and shortening of the upper beak; and shortening disfigurement, and gangrene of the toes. Two phototoxic furocoumarins, oxypeucedanin and isoimperitorin, were isolated from C. longipes seed. Either compound, administered orally, produced photosensitivity in 2-week-old chicks.
两周龄的未经雌雄鉴别白肉鸡雏鸡和两周龄的未经雌雄鉴别白火鸡雏，分别按体重的0.4%、0.8%和1.6%投喂沃森翼叶芹种子或全株、或长柄翼叶芹种子，然后每天置于阳光下5小时，持续7天。所有植物材料均使雏鸡产生中度至重度光敏反应。中毒症状包括畏光；喙、鸡冠和足部发红；眶周脱毛；鸡冠和喙边缘有干燥的浆液性液体；角膜结膜炎；以及足部和腿部出现多处病变。火鸡雏表现出与雏鸡相似的综合征。喂食长柄翼叶芹种子的火鸡死亡率特别高。治疗6周后火鸡的中毒症状包括腿部震颤；上喙上翘和缩短；脚趾缩短变形和坏疽。从长柄翼叶芹种子中分离出两种光毒性呋喃香豆素，氧化前胡素和异欧前胡素。口服这两种化合物中的任何一种，均可使两周龄雏鸡产生光敏反应。
