Baklaja R, Cuperlović K, Jovanović B, Cvetković V, Kezić J, Rasović N, Stojimirović E, STajić M
Bilt Hematol Transfuz. 1977;5(2):63-70.
Immunological examination of F VIII related antigen gave some new information on the nature of congenital defects of F VIII, in haemophilia A and von Willenrand's disease. Besides classic method in diagnostics of von Willebrand's disease, the determination of F VIII related antigen can be used as a diagnostic criterium in distinguishing von Willebrand's disease from some mild forms of haemophilis, as well as in detection of haemophilia carrier. In addition, the study on the relationship of immunological value of F VIII related antigen and biological activity of F VIII offers more data on the possibility of detection of so-called "hypercoagulability" and states proceeding thrombosis. The method for determination of F VIII related antigen (Rocket electrophoresis--Laurel) as well as the values of F VIII in health persons of our population is described in this paper.
对血友病A和血管性血友病中F VIII相关抗原的免疫学检测为F VIII先天性缺陷的本质提供了一些新信息。除了诊断血管性血友病的经典方法外，F VIII相关抗原的测定可作为区分血管性血友病与某些轻度血友病形式以及检测血友病携带者的诊断标准。此外，对F VIII相关抗原免疫值与F VIII生物活性之间关系的研究为检测所谓的“高凝性”和血栓形成相关状态提供了更多数据。本文描述了F VIII相关抗原（火箭电泳 - 劳雷尔法）的测定方法以及我国健康人群中F VIII的值。
