红细胞膜中胆固醇的跨膜迁移（“翻转”）
Transmembrane migration ('flip-flop') of cholesterol in erythrocyte membranes.
作者信息
Kirby C, Green C
出版信息
Biochem J. 1977 Dec 15;168(3):575-7. doi: 10.1042/bj1680575.
Abstract
After exchange with [14C]cholesterol-labelled plasma lipoproteins for 0.5-4h, erythrocytes were extracted with bile-salt solutions. The extracted cholesterol (mainly from the outside of the erythrocyte membrane) had the same specific radioactivity as the residual sterol. Thus cholesterol equilibrates rapidly (half-time less than 1 h) between the two sides of the membrane.
摘要
在用[14C]胆固醇标记的血浆脂蛋白进行0.5 - 4小时的交换后，用胆盐溶液提取红细胞。提取出的胆固醇（主要来自红细胞膜的外侧）与残留固醇具有相同的比放射性。因此，胆固醇在膜的两侧之间迅速达到平衡（半衰期小于1小时）。
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