亚甲蓝对兔红细胞中谷氨酸和还原型谷胱甘肽的影响。
Effect of Methylene Blue on glutamate and reduced glutathione of rabbit erythrocytes.
作者信息
Smith J E, Mahaffey E, Lee M
出版信息
Biochem J. 1977 Dec 15;168(3):587-9. doi: 10.1042/bj1680587.
Abstract
Methylene Blue injected into rabbits resulted in increased glutamate, reduced glutathione and pyrrolid-2-one-5-carboxylate in erythrocytes. The increase in reduced glutathione was probably due to increased glutamate changing the feedback control of glutathione on gamma-glutamylcysteine synthetase.
摘要
向兔子体内注射亚甲蓝会导致红细胞中谷氨酸增加、谷胱甘肽减少以及吡咯烷-2-酮-5-羧酸盐减少。还原型谷胱甘肽的增加可能是由于谷氨酸增加改变了谷胱甘肽对γ-谷氨酰半胱氨酸合成酶的反馈控制。
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Effect of Methylene Blue on glutamate and reduced glutathione of rabbit erythrocytes.亚甲蓝对兔红细胞中谷氨酸和还原型谷胱甘肽的影响。
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The effect of methylene blue and diaminodiphenysulfone on red cell reduced glutathione synthesis.亚甲蓝和二氨基二苯砜对红细胞还原型谷胱甘肽合成的影响。
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Methylene blue directly oxidizes glutathione without the intermediate formation of hydrogen peroxide.亚甲蓝直接氧化谷胱甘肽，不会中间形成过氧化氢。
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Interactions between methylene blue and erythrocytes of several mammalian species, in vitro.
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Oxidation of glutathione by methylene blue is equivalent in G-6-PD deficient and normal erythrocytes.在葡萄糖-6-磷酸脱氢酶（G-6-PD）缺乏的红细胞和正常红细胞中，亚甲蓝对谷胱甘肽的氧化作用是相同的。
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[Research in vivo on the action of methylene blue on erythrocytes].[亚甲蓝对红细胞作用的体内研究]
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[The behavior of reduced glutathione (GSH) in erythrocytes during Heinz body formation].[海因茨小体形成过程中红细胞内还原型谷胱甘肽（GSH）的行为]
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Methylene blue and erythrocytes in the living animal. Contribution to the toxicology of methylene blue and formation of Heinz bodies.活体动物体内的亚甲蓝与红细胞。对亚甲蓝毒理学及海因茨小体形成的贡献。
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The effect of methylene blue and diaminodiphenysulfone on red cell reduced glutathione synthesis.亚甲蓝和二氨基二苯砜对红细胞还原型谷胱甘肽合成的影响。
J Lab Clin Med. 1972 Oct;80(4):481-7.
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Relationship of in vivo erythrocyte glutathione flux to the oxidized glutathione transport system.体内红细胞谷胱甘肽通量与氧化型谷胱甘肽转运系统的关系。
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Studies in the enzymology of glutathione metabolism in human erythrocytes.人类红细胞中谷胱甘肽代谢的酶学研究。
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