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一种巯基抑制剂对体外骨髓集落(CFU-c)的影响。

Effect of a sulfhydryl inhibitor on in vitro bone marrow colonies (CFU-c).

作者信息

Shellhaas J, Filppi J, Rheins M

出版信息

Biomedicine. 1977 Dec;27(9-10):335-7.

PMID:606308
Abstract

A dose-related increase in the number of in vitro colony-forming units. CFU-c, was observed in mouse bone marrow cell suspensions following the administration of the sulfhydryl inhibitor, sodium iodoacetate. No effect on CFU-s was observed at the dosages and the periods selected for examination. Direct exposure of marrow cells in vitro to various concentrations of iodoacetate did not influence colony formation.

摘要

给予巯基抑制剂碘乙酸钠后,在小鼠骨髓细胞悬液中观察到体外集落形成单位(CFU-c)的数量呈剂量相关增加。在所选择用于检查的剂量和时间段内,未观察到对CFU-s有影响。体外将骨髓细胞直接暴露于不同浓度的碘乙酸盐中并不影响集落形成。

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Experientia. 1979 Oct 15;35(10):1400-1. doi: 10.1007/BF01964033.