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巯基化合物对红细胞生成的剂量相关增强作用及其被硫醇抑制剂逆转的情况。

Dose-related enhancement of erythropoiesis by sulfhydryl compounds and its reversal with a thiol inhibitor.

作者信息

Pourreau-Schneider N

出版信息

Experientia. 1979 Oct 15;35(10):1400-1. doi: 10.1007/BF01964033.

DOI:10.1007/BF01964033
PMID:499440
Abstract

Erythropoietin-mediated erythrocyte development from bone marrow of hypertransfused rats was significantly greater when the culture medium contained an optimal dose of certain sulfhydryls. This stimulatory action was attributed to the presence of SH groups because erythroblast numbers fell to control levels when the culture contained the thiol inhibitor, p-hydroxymercuribenzoate.

摘要

当培养基中含有最佳剂量的某些巯基时,促红细胞生成素介导的高输血大鼠骨髓红细胞发育显著增强。这种刺激作用归因于巯基的存在,因为当培养物中含有硫醇抑制剂对羟基汞苯甲酸时,成红细胞数量降至对照水平。

相似文献

1
Dose-related enhancement of erythropoiesis by sulfhydryl compounds and its reversal with a thiol inhibitor.巯基化合物对红细胞生成的剂量相关增强作用及其被硫醇抑制剂逆转的情况。
Experientia. 1979 Oct 15;35(10):1400-1. doi: 10.1007/BF01964033.
2
Creatine kinase reactivation by thiol compounds.
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Arch Biochem Biophys. 1975 Feb;166(2):400-16. doi: 10.1016/0003-9861(75)90403-8.
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Contrasting effects of various sulfhydryl reagents on the activity of lecithin: cholesterol acyltransferase.各种巯基试剂对卵磷脂:胆固醇酰基转移酶活性的对比作用。
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本文引用的文献

1
Studies on erythropoiesis. IX. Mechanism of decreased erythropoiesis in experimental polycythemia.红细胞生成的研究。IX. 实验性红细胞增多症中红细胞生成减少的机制。
Proc Soc Exp Biol Med. 1958 Aug-Sep;98(4):789-93. doi: 10.3181/00379727-98-24187.
2
Erythroid colony formation in cultures of mouse and human bone marrow: analysis of the requirement for erythropoietin by gel filtration and affinity chromatography on agarose-concanavalin A.小鼠和人骨髓培养中的红系集落形成:通过琼脂糖-伴刀豆球蛋白A凝胶过滤和亲和层析分析对促红细胞生成素的需求
J Cell Physiol. 1974 Apr;83(2):309-20. doi: 10.1002/jcp.1040830218.
3
In vitro growth promotion of rat leukemia L5222 cells in the presence of 2-mercaptoethanol.
在2-巯基乙醇存在的情况下大鼠白血病L5222细胞的体外生长促进作用
J Natl Cancer Inst. 1975 Dec;55(6):1467-70. doi: 10.1093/jnci/55.6.1467.
4
Erythroid progenitors in mouse bone marrow detected by macroscopic colony formation in culture.通过培养中的宏观集落形成检测小鼠骨髓中的红系祖细胞。
Exp Hematol. 1975 Jan;3(1):32-43.
5
Relationship between inhibition of membrane SH groups and hemolysis induced by SH inhibitors.膜SH基团抑制与SH抑制剂诱导的溶血之间的关系。
Jpn J Pharmacol. 1977 Aug;27(4):596-9. doi: 10.1254/jjp.27.596.
6
Erythropoiesis: comparison of in vivo and in vitro amplification.
Blood Cells. 1978;4(1-2):155-74.
7
Effect of a sulfhydryl inhibitor on in vitro bone marrow colonies (CFU-c).一种巯基抑制剂对体外骨髓集落(CFU-c)的影响。
Biomedicine. 1977 Dec;27(9-10):335-7.
8
[In vitro studies on amplification of rat erythropoiesis (author's transl)].大鼠红细胞生成扩增的体外研究(作者译)
Nouv Rev Fr Hematol Blood Cells. 1977 May-Jun;18(3):627-31.