Mitchell J C
Contact Dermatitis. 1977 Dec;3(6):315-20. doi: 10.1111/j.1600-0536.1977.tb03695.x.
Thirty-five patients who showed 90 one plus (+) patch test reactions to 28 patch test chemicals at Day 2 (D2) were retested to the chemicals at D7. On retesting, 60% (54/90) reactions were positive but 42% (38/90) were negative at D9, suggesting that false positive patch test reactions were common when more than one positive reaction was obtained by concomitant patch testing. On retesting, the total % positivity was reduced from 344 to 241 suggesting that the true index of sensitivity was falsely exaggerated by concomitant testing.
35名患者在第2天(D2)对28种斑贴试验化学物质出现90次一级(+)斑贴试验反应,在第7天对这些化学物质进行了重新测试。重新测试时,60%(54/90)的反应在第9天呈阳性,但42%(38/90)呈阴性,这表明当通过同时进行斑贴试验获得多个阳性反应时,假阳性斑贴试验反应很常见。重新测试时,阳性总百分比从344降至241,这表明同时测试会错误地夸大真正的敏感性指标。