奥迪括约肌与胃、十二指肠和胆囊的关系。
The relationship of the sphincter of Oddi to the stomach, duodenum and gall-bladder.
作者信息
Wyatt A P
出版信息
J Physiol. 1967 Nov;193(2):225-43. doi: 10.1113/jphysiol.1967.sp008354.
Flow through the sphincter of Oddi was studied by a constant-pressure perfusion apparatus, and by using a constant rate of infusion and measuring pressure changes just proximal to the sphincter. Pressure changes from balloons placed in the gastric antrum and duodenum were recorded. Despite considerable variation in activity and behaviour, the following conclusions were reached.1. The sphincter of Oddi appears to be partially autonomous but is readily affected by changes in duodenal tone.2. Reflex inhibition of the sphincter of Oddi is seen on electrical and mechanical stimulation of the gall-bladder but not with passive pressure changes within the gall-bladder.3. This reflex is relayed through the coeliac ganglion.4. There is a definite relationship between gastric antral activity and flow through the sphincter of Oddi. This is more obvious when food is present in the stomach.5. Mechanical or electrical stimulation of the stomach, duodenum, or upper small bowel influences the tone of the sphincter of Oddi.
采用恒压灌注装置，通过以恒定速率输注并测量Oddi括约肌近端的压力变化，对通过Oddi括约肌的血流进行了研究。记录了置于胃窦和十二指肠的气囊的压力变化。尽管活动和行为存在相当大的差异，但得出了以下结论。1. Oddi括约肌似乎部分自主，但很容易受到十二指肠张力变化的影响。2. 对胆囊进行电刺激和机械刺激时，可观察到Oddi括约肌的反射性抑制，但胆囊内被动压力变化时则无此现象。3. 该反射通过腹腔神经节传导。4. 胃窦活动与通过Oddi括约肌的血流之间存在明确关系。当胃中有食物时，这种关系更为明显。5. 对胃、十二指肠或上小肠进行机械或电刺激会影响Oddi括约肌的张力。
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