Folland E D, Hamilton G W, Larson S M, Kennedy J W, Williams D L, Ritchie J L
J Nucl Med. 1977 Dec;18(12):1159-66.
Left-ventricular ejection fraction (EF) can be measured by several radionuclide methods. The EFs determined by three such methods (first-transit time-activity, equilibrium blood-pool time-activity, and equilibrium blood-pool area-length) were compared in 30 patients with EFs measured by area-length analysis of x-ray contrast angiograms. Both time-activity methods (first-transit and blood-pool) yielded EFs that correlated well with x-ray contrast EFs (r=0.86 and 0.84, respectively). Area-length analysis of blood-pool images yielded EFs that agreed less well with x-ray contrast EFs (r=0.73 in the RAO view, 0.70 in the LAO view). We conclude that first-transit and blood-pool techniques are equally accurate methods for determining EF when the time-activity method of analysis is employed.
左心室射血分数（EF）可通过多种放射性核素方法进行测量。在30例患者中，比较了三种此类方法（首次通过时间-活性法、平衡血池时间-活性法和平 衡血池面积-长度法）所测定的EF值与通过X线造影血管造影面积-长度分析测定的EF值。两种时间-活性法（首次通过法和血池法）所测得的EF值与X线造影EF值相关性良好（分别为r = 0.86和0.84）。血池图像的面积-长度分析所测得的EF值与X线造影EF值的一致性较差（右前斜位视图中r = 0.73，左前斜位视图中r = 0.70）。我们得出结论，当采用时间-活性分析方法时，首次通过法和血池法是测定EF的同等准确的方法。
