Bohdanecka M, Bohdanecky Z, Jarvik M E
Science. 1967 Jul 21;157(3786):334-6. doi: 10.1126/science.157.3786.334.
A small acute brain puncture produced retrograde amnesia in a passive avoidance learning situation in mice. If injury to the hippocampus was inflicted either immediately, 1 hour after the learning, or 1 hour before the learning, the animals showed a retention deficit; the degree of this deficit was related to the time interval. No effect of this injury was observed on retest performance when the animals were treated as long as 6 hours before or after the learning trial.
在小鼠的被动回避学习情境中，一次小型急性脑穿刺导致了逆行性遗忘。如果在学习后1小时、学习前1小时或学习的同时立即损伤海马体，动物会表现出记忆保持缺陷；这种缺陷的程度与时间间隔有关。当在学习试验前或后长达6小时对动物进行处理时，未观察到这种损伤对重测表现有任何影响。
