Barbacid M, Stephenson J R, Aaronson S A
Nature. 1976 Aug 12;262(5569):554-9. doi: 10.1038/262554a0.
The translation product of the gag gene of mammalian type-c- RNA viruses is a 65,000-68,000 molecular weight precursor polypeptide (Pr65) whose cleavage leads to the formation of four virion proteins, p30, p15, p12 and p10. An immunological approach has been used to establish the arrangement of the sequences coding for these proteins within the viral genome as (5') p15-p12-p30-p10 (3').
哺乳动物C型RNA病毒gag基因的翻译产物是一种分子量为65,000 - 68,000的前体多肽(Pr65),其切割后会形成四种病毒粒子蛋白,即p30、p15、p12和p10。已采用免疫学方法确定病毒基因组中编码这些蛋白的序列排列为(5')p15 - p12 - p30 - p10(3')。