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碳酸酯和氨基甲酸酯的合成、药理学及毒理学研究

Synthesis, pharmacologic and toxicologic study of carbonic and carbamic acid esters.

作者信息

Avramova P, Dryanovska L, Ilarionov Y

出版信息

Pharmazie. 1977 Oct;32(10):575-7.

PMID:607214
Abstract

The results of the pharmacologic study of some synthesized derivatives of carbamic and carbonic acids show that the compounds are biologically active. They are less toxic than imipramine, and exert a marked excitation effect on the central nervous system. Some of the compounds (including PS-1, P-8-Y and PS-4) possess greater antidepressive action than imipramine.

摘要

对一些氨基甲酸和碳酸合成衍生物的药理研究结果表明,这些化合物具有生物活性。它们的毒性比丙咪嗪小,并对中枢神经系统产生显著的兴奋作用。其中一些化合物(包括PS - 1、P - 8 - Y和PS - 4)具有比丙咪嗪更强的抗抑郁作用。

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