Synthesis and N.M.R. study of trans 2-phenoxycyclohexanol and some of its derivatives with potential antiinflammatory activity.

A number of amino-ethers, acids, amino-esters, amino-amides and carbamates was synthesized from trans-2-phenoxycyclohexanol. The configuration of the starting material was established by N.M.R. spectroscopy. Pharmacological tests showed an antiinflammatory activity for some of the derivatives.