Santavuori P, Erkkilä H
Neuropadiatrie. 1976 Aug;7(3):283-301. doi: 10.1055/s-0028-1091630.
In ophthalmoscopy, optic disc drusen often bear a fallacious resemblance to true papilloedema and some of those affected have neurological disorders. Adequate realization among neuropaediatricians of the relation between drusen and these disorders may save some children from neuroradiological and neurosurgical investigations, often considered unavoidable for exclusion of an intracranial process. Systematic evaluation in a series of 50 children with optic disc drusen showed that neurological disorders are common even in subjects brought to examination for other reasons than neurological symptoms. The findings showed accumulation into two subgroups. There was a group of 15 clumsy children with learning difficulties and delayed development of speech. Another group consisted of 20 children with sudden convulsions and/or headache and vomiting, and with EEG abnormalities but otherwise normal neurological findings. In addition, there were a subgroup with miscellaneous abnormalities and a minor group of children in whom no abnormalities were found except for the eye anomaly.
在检眼镜检查中，视盘玻璃疣常常与真正的视乳头水肿有相似的假象，并且一些患者伴有神经功能障碍。神经儿科医生充分认识到玻璃疣与这些疾病之间的关系，可能会使一些儿童避免进行神经放射学和神经外科检查，而这些检查通常被认为是排除颅内病变时不可避免的。对50例视盘玻璃疣患儿进行的系统评估显示，即使是因非神经症状前来检查的患儿，神经功能障碍也很常见。研究结果分为两个亚组。一组有15名患儿，表现为笨拙、学习困难和语言发育迟缓。另一组由20名患儿组成，他们有突然惊厥和/或头痛、呕吐，脑电图异常，但其他神经学检查结果正常。此外，还有一个有各种异常的亚组和一小部分除眼部异常外未发现其他异常的患儿。
