Talbert L M, Pearlman W H, Potter H D
Am J Obstet Gynecol. 1977 Dec 1;129(7):781-7. doi: 10.1016/0002-9378(77)90397-0.
The levels of corticosteroid-binding globulin (CBG, transcortin), total cortisol, and unbound cortisol were measured in maternal and fetal serum at the time of cesarean section or vaginal delivery. While the total cortisol levels in maternal serum do not differ significantly in vaginal delivery as compared to cesarean section, cord serum cortisol levels are significantly higher after vaginal delivery. There are no differences associated with the route of delivery between the mean levels of CBG in cord and maternal blood. However, after the vaginal delivery the unbound cortisol level in maternal serum is more than twice as high as that at cesarean section and in cord serum it is seven times as high. These changes reflect changes in total cortisol and may represent a prelabor surge of fetal cortisol production, or a stress response associated with labor, or a combination of both.
在剖宫产或阴道分娩时，测量母体和胎儿血清中皮质类固醇结合球蛋白（CBG，皮质素转运蛋白）、总皮质醇和游离皮质醇的水平。与剖宫产相比，阴道分娩时母体血清中的总皮质醇水平无显著差异，但阴道分娩后脐血血清皮质醇水平显著更高。脐血和母体血液中CBG的平均水平在分娩方式上无差异。然而，阴道分娩后母体血清中游离皮质醇水平比剖宫产时高出两倍多，在脐血血清中则高出七倍。这些变化反映了总皮质醇的变化，可能代表胎儿皮质醇产生的产前激增，或与分娩相关的应激反应，或两者兼而有之。
