Wilson P D, Benham F, Franks L M
Cell Biol Int Rep. 1977 May;1(3):229-38. doi: 10.1016/0309-1651(77)90047-9.
The cytochemical localisation and presumed isoenzyme type (based on selective inhibition experiments) of alkaline phosphatase in 5 cell lines derived frrom normal human, rat, mouse and hamster tissues, 6 human lymphoblastoid lines and 6 human and mouse tumour-derived cell lines are described. Enzyme activity varied between the cell lines. An isoenzyme inhibited by L-phenylalanine was present in 3 normal lines, 3 lymphoblastoid lines and 2 tumour lines. The presence of this isoenzyme cannot be used as a marker of neoplastic transformation.
本文描述了从正常人、大鼠、小鼠和仓鼠组织衍生的5种细胞系、6种人淋巴母细胞系以及6种人源和鼠源肿瘤衍生细胞系中碱性磷酸酶的细胞化学定位和推测的同工酶类型（基于选择性抑制实验）。各细胞系之间的酶活性有所不同。一种受L-苯丙氨酸抑制的同工酶存在于3种正常细胞系、3种淋巴母细胞系和2种肿瘤细胞系中。这种同工酶的存在不能用作肿瘤转化的标志物。
