Kinetic considerations relating to the use of drug precursors.
作者信息
Martin B K
出版信息
Br J Pharmacol Chemother. 1967 Nov;31(3):420-34. doi: 10.1111/j.1476-5381.1967.tb00409.x.
Abstract
摘要
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Kinetic considerations relating to the use of drug precursors.与药物前体使用相关的动力学考量。
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Understanding the pharmacokinetics of prodrug and metabolite.了解前药和代谢物的药代动力学。
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本文引用的文献
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Drug latentiation.药物潜伏化
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EXCRETION AND THE ACCRUAL OF DRUG METABOLITES.药物代谢产物的排泄与蓄积
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Dosage schedule and pharmacokinetics in chemotherapy.化疗中的给药方案与药代动力学
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Sulfaethylthiadiazole. IV. Steady state blood concentration and urinary excretion data following repeated oral doses.
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Proguanil, the isolation of a metabolite with high antimalarial activity.氯胍，一种具有高抗疟活性代谢物的分离。
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Kinetic considerations relating to the accrual and elimination of drug metabolites.与药物代谢物的累积和消除相关的动力学考量。
Br J Pharmacol Chemother. 1967 Feb;29(2):136-49. doi: 10.1111/j.1476-5381.1967.tb01947.x.
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Blood levels of drug at the equilibrium state after multiple dosing.多次给药后达到平衡状态时药物的血药浓度。
Nature. 1965 Sep 18;207(5003):1301-2. doi: 10.1038/2071301a0.
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The role of the therapeutic regimen in dosage design. II.治疗方案在剂量设计中的作用。II.
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