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[长时间分次照射后大鼠骨髓和脾脏核酸代谢在较长间隔时间的再生]

[Regeneration of nucleic acid metabolism in rat bone marrow and spleen at prolonged intervals after lengthy fractionated irradiation].

作者信息

Kisel'gof E I, Rogacheva S A, Mushkacheva G S

出版信息

Radiobiologiia. 1984 Nov-Dec;24(6):817-20.

PMID:6083579
Abstract

A study was made of the content and rate of biosynthesis of nucleic acids in the bone marrow and spleen, the mitotic activity of splenocytes and the lienogram of rats during a year after the end of fractionated irradiation with cumulative doses of 9.7 and 19.4 Gy. It was shown that the completeness of restoration of the parameters changed by irradiation depended upon radiation dose received by the animals. Inhibition of proliferative processes in the bone marrow was noted a year after irradiation with a dose of 19.4 Gy.

摘要

对大鼠进行累积剂量为9.7和19.4 Gy的分次照射后一年,研究了其骨髓和脾脏中核酸的生物合成含量和速率、脾细胞的有丝分裂活性以及脾脏造影。结果表明,照射所改变参数的恢复程度取决于动物接受的辐射剂量。在接受19.4 Gy剂量照射一年后,观察到骨髓中增殖过程受到抑制。

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