Kaiser E
Geburtshilfe Frauenheilkd. 1984 Oct;44(10):651-5. doi: 10.1055/s-2008-1036324.
The activity of Neo-Eunomin on androgenisation of the skin, seborrhoea, acne, alopecia and hirsutism was investigated in a long-term trial covering 165 patients over 3379 cycles. The age of the patients ranged from 19 to 47 years. The first three symptoms showed clear improvement after 6 months of treatment, and in many cases a cure was achieved after 12 months of therapy. No equally good results could at least be obtained in the treatment of hirsutism. In a further study Neo-Eunomin was compared with a contraceptive containing a nor-testosteron derivative (Conceplan 21). Neo-Eunomin showed convincingly better efficacy in the treatment of androgenisation of the skin than the preparation under comparison.
在一项针对165名患者、涵盖3379个周期的长期试验中,研究了新戊诺明对皮肤雄激素化、脂溢性皮炎、痤疮、脱发和多毛症的作用。患者年龄在19至47岁之间。治疗6个月后,前三种症状有明显改善,在许多情况下,治疗12个月后实现了治愈。至少在多毛症的治疗中未能取得同样好的效果。在另一项研究中,将新戊诺明与一种含有诺睾酮衍生物的避孕药(康赛普兰21)进行了比较。在治疗皮肤雄激素化方面,新戊诺明的疗效明显优于对照制剂。