Belaube P, Devaux J, Gamby T, Garcin G, Privat Y
Sem Hop. 1982 Jul 1;58(26-27):1650-3.
It has been established that, through skin responds to circulating androgens, it can also produce androgens from precursors. Therapy can address either of the two following physiopathological steps: the secretory step can be countered by replacement or suppressive therapy which is now fairly well mastered; the target-organ step opens new possibilities concerning receptor abnormalities and receptor control. The medical literature was reviewed for data on hormonal therapy for women with acne, idiopathic hirsutism and seborrheic alopecia, three conditions which are usually only partially improved by cosmetic treatment.
已经证实，皮肤不仅会对循环中的雄激素产生反应，还能从前体物质生成雄激素。治疗可以针对以下两个病理生理步骤中的任何一个：分泌步骤可以通过替代或抑制疗法来对抗，目前这方面已相当成熟；靶器官步骤在受体异常和受体控制方面开辟了新的可能性。我们查阅了医学文献，以获取有关痤疮、特发性多毛症和脂溢性脱发女性激素治疗的数据，这三种病症通常仅通过美容治疗只能得到部分改善。
