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主动脉缩窄手术:对253例患者的九年回顾

Surgery of coarctation of the aorta: a nine-year review of 253 patients.

作者信息

Anyanwu E, Klemm C, Achatzy R, Jelesijevic V, Löser H, Müller U S, Greve H, Dittrich H

出版信息

Thorac Cardiovasc Surg. 1984 Dec;32(6):350-7. doi: 10.1055/s-2007-1023422.

Abstract

From 1973 to 1982, 253 patients--164 males and 89 females--underwent an operation for coarctation of the aorta in our clinic. Of the patients 72.3% presented with a circumscribed lesion and 58.5% with associated congenital cardiovascular defects. Resection with end-to-end anastomosis was performed in 138 patients (54.5%). Seventy-four patients (29.3%) had vascular graft prosthesis, 1.2% underwent the Clagett's operation, 9.1%, the indirect isthmoplasty and the rest (5.9%), the subclavian flap plastic. Ventricular fibrillation led to the intraoperative death of 3 infants with associated intracardiac and multiple somatic defects. The operative mortality was high in children under 15 months (13.2%), 1% in all the others taken together and 0% in all cases without concomitant lesions. Paraplegia occurred in only one patients (0.4%). One hundred twenty-eight patients were followed-up over a mean period of 3.6 years. The systolic and diastolic pressures decreased by a mean of 30 mmHg and 15 mmHg respectively. Eighty-seven patients (68%) had normal blood pressure at the time of examination. The rest (41 patients) had persistent postoperative hypertension necessitating medical management. The surgical technique elected did not influence the level and incidence of persistent postoperative hypertension, rather the level of the preoperative systolic right arm-to-leg pressure gradient (SPG) related closely to the incidence of persistent hypertension. Thirty patients (23.4%), among whom were 24 children under 10 years--some of them with preductal hypoplasia--presented with an SPG above 20 mmHg.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

1973年至1982年期间,我院对253例主动脉缩窄患者实施了手术,其中男性164例,女性89例。患者中72.3%表现为局限性病变,58.5%伴有先天性心血管缺陷。138例患者(54.5%)行端端吻合切除术。74例患者(29.3%)使用了血管移植假体,1.2%接受了克拉杰特手术,9.1%接受了间接峡部成形术,其余患者(5.9%)接受了锁骨下皮瓣整形术。3例伴有心内和多种躯体缺陷的婴儿因室颤术中死亡。15个月以下儿童手术死亡率较高(13.2%),其他所有患者手术死亡率为1%,无合并病变的所有病例手术死亡率为0%。仅1例患者(0.4%)发生截瘫。128例患者接受了平均3.6年的随访。收缩压和舒张压平均分别下降30 mmHg和15 mmHg。87例患者(68%)检查时血压正常。其余41例患者术后持续高血压,需要药物治疗。所选择的手术技术并未影响术后持续高血压的水平和发生率,术前收缩期右臂与下肢压力梯度(SPG)水平与持续高血压的发生率密切相关。30例患者(23.4%)的SPG高于20 mmHg,其中24例为10岁以下儿童,部分患儿有导管前发育不全。(摘要截选至250字)

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