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出生后第一个月内矫正的主动脉缩窄。

Coarctation of the aorta corrected during the first month of life.

作者信息

Ehrhardt P, Walker D R

机构信息

Killingbeck Hospital, Leeds.

出版信息

Arch Dis Child. 1989 Mar;64(3):330-2. doi: 10.1136/adc.64.3.330.

Abstract

Forty eight children (29 boys) had surgical correction of coarctation of the aorta during the first month of life; all had patent ductus arteriosus. The 33 survivors were reviewed at a mean age of 6.6 years. Of the 19 children with no associated anomaly, none had died. The more complex the associated anomalies, the greater the mortality. Two (6%) of the survivors, both with associated anomalies, have some residual disability; one is incapable of leading an independent life. No survivor has systemic hypertension. Six (18%) of the survivors have required correction of recurrent coarctation, and one is awaiting repair. Newborn babies suspected of having coarctation should be assessed for surgical correction without delay, and medical treatment (including, if necessary, infusion of prostaglandin E2 in a dose of 0.025 micrograms/kg/minute) should be instituted in the interim. Long term follow up is important to detect systemic hypertension or recurrence of the coarctation. This occurred in seven (21%) of our survivors.

摘要

48名儿童(29名男孩)在出生后的第一个月接受了主动脉缩窄的外科矫正手术;所有患儿均有动脉导管未闭。对33名幸存者进行了复查,平均年龄为6.6岁。在19名无相关异常的儿童中,无一死亡。相关异常越复杂,死亡率越高。两名(6%)幸存者均有相关异常,存在一些残留残疾;其中一名无法独立生活。没有幸存者患有系统性高血压。六名(18%)幸存者需要对复发性主动脉缩窄进行矫正,一名正在等待修复。怀疑患有主动脉缩窄的新生儿应立即进行手术矫正评估,并在此期间进行药物治疗(如有必要,以0.025微克/千克/分钟的剂量输注前列腺素E2)。长期随访对于检测系统性高血压或主动脉缩窄复发很重要。这在我们的七名(21%)幸存者中发生了。

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