Tuncer M
Arch Int Physiol Biochim. 1984 Oct;92(3):227-31. doi: 10.3109/13813458409104503.
The interaction of metoclopramide and two dopaminergic agonists, dopamine and apomorphine, was investigated on ganglionic transmission at the superior cervical ganglion of the anaesthetized cat. Dopamine (100 micrograms, i.a.) and apomorphine (100 micrograms, i.a.) decreased the height of action potential induced by supramaximal preganglionic stimulation. Metoclopramide (3 mg/kg, i.v.) antagonized the inhibition caused by dopamine and apomorphine. But it did not alter the transmission block caused by hexamethonium (100 micrograms, i.a.) or noradrenaline (100 micrograms, i.a.). The results suggest that dopamine-induced inhibition of the ganglionic transmission is related to the activation of dopaminergic receptors of the ganglion cells.
研究了胃复安与两种多巴胺能激动剂多巴胺和阿扑吗啡在麻醉猫颈上神经节神经节传递中的相互作用。多巴胺（100微克，动脉注射）和阿扑吗啡（100微克，动脉注射）降低了由超强节前刺激诱导的动作电位高度。胃复安（3毫克/千克，静脉注射）拮抗了多巴胺和阿扑吗啡引起的抑制作用。但它并未改变六甲铵（100微克，动脉注射）或去甲肾上腺素（100微克，动脉注射）引起的传递阻滞。结果表明，多巴胺诱导的神经节传递抑制与神经节细胞多巴胺能受体的激活有关。
